We comply with the HONcode standard for trustworthy health information -, Direction and dosage information for Bravecto. It is the same product (made by the same manufacturer) but with a different name. In well-controlled laboratory studies, Bravecto demonstrated ≥ 93% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus ticks 48 hours post-infestation for 12 weeks. How Long Until Maximum Effect Against Fleas Is Reached? BECAUSE THEY NEED YOU MORE THAN THEY WOULD LIKE TO ADMIT. Simparica vs. Bravecto Similarities. Other Parasites Killed, Controlled or Repelled, Manufacturer recommends against use but not specifically labeled against, Hookworms, Roundworms, Whipworms & Heartworm, Manufacturer recommends consulting with veterinarian first, Begins Killing Fleas in 4 hours,99% Fleas Dead within 8 hours, Demodectic Mange Mites, Ticks, Sarcoptic Mange Mites, Dogs: Ticks, Ear Mites, Sarcoptic Mange Mites & Heartworm LarvaeCats: Hookworms, Roundworms, Ear Mites & Heartworm Larvae, Greater than 98% of Pre-Existing Fleas Dead within 24 Hours; Then New Fleas Greater than 93.8% within 12 hours, Ticks, Hookworms, Roundworms, Ear Mites, Heartworm, 98% of Pre-Existing Fleas Dead in 12 Hours; Then New Fleas in 2 Hours, Dogs: Whipworms, Hookworms, Roundworms & Heartworm Cats: Hookworms, Roundworms, Ear Mites & Heartworm, daily or as needed (but not more than once a day), 90% of fleas dead in 6 hours, 99% in 12 hours, Frontline, Fiproguard, PetArmor EasySpot (cats) Parastar (dogs) Effipro (cats), 24 Hrs to Translocate, then 4-18 Hours to Kill Fleas, 24 Hrs to Translocate, then 4-18 Hrs to Kill Fleas and 24-48 Hours to Kill Ticks, 99.9% of fleas dead in 72 hours (66% of fleas dead in 24 hours), Ticks, Sarcoptic Mange Mites, Demodectic Mange mites, 12 Weeks(only kills Lone Star ticks for 8 weeks), every 12 weeks for fleas(every 8 weeks for ticks), >96.2% of fleas dead within 8 hours, begins to kills fleas after 3 hours, 24 hours (after that new fleas killed within 2 hours), Ticks, Lice, aids in Sarcoptic Mange control, 8 months (5 months if pet swimsor bathes once a month or more),30 days for lice, Monthly for oral; Every 6 Months for Injectable, Individual ingredients Yes, but combination not approved, Prescription Drug, Non-Prescription Drug or Insectcide, Lethal Dose to 50% of the Population(the higher the number, the safer the product)[What is LD50? However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. BRAVECTO Topical Solution for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. PROVECTA FOR CATS. Fleas tend to get more active when this product works on them so tend to be more visible. Keep this and all drugs out of the reach of children. Bravecto ® for Dogs is available in two variants: Bravecto ® Chew and Bravecto ® Spot-On for Dogs. Pyriproxifen (flea sterilizer) Dog. Because there are 27 different products compared in 16 different categories, we have split up the information into 4 separate tables. Dogs love the pork flavor and eat tablets like treats. Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Provecta Advanced for Dogs is a once-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II. There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). Dosage. Bravecto for dogs is a chewable tablet that delivers 12 weeks of flea and tick protection. You can administer Bravecto any time, day or night, but it’s best to give him the pork-flavored tablet around feeding time. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Provecta Advanced for Dogs is a once-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II. Bravecto Chew for Dogs is approved for use in breeding, pregnant, and lactating dogs. Not for human use. Additional information can be found at www.bravecto.com. A single dose of Bravecto ® Chew is given to your dog orally, with food. Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product. Bravecto: in a field study of 294 dogs, reactions included vomiting, decreased appetite, diarrhea, lethargy, and increased drinking. 3850 Grand View Blvd. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Distributed by: Intervet Inc (d/b/a Merck Animal Health), Summit, NJ 07901. Dermal Dose: >5,000 mg/kg in rats Orally: 450 mg/kg in rats, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >4,000 mg/kg in rats for Permethrin, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >2,000 mg/kg in rabbits for Moxidectin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats; >4,000 mg/kg in rats for topical Permethrin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats Methoprene Orally: >34,600 in rats (virtually non-toxic), Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats, Indoxacarb must be activated by insect metabolism (no activity in mammals), Indoxacarb is inert in the mammal body, >4,000 mg/kg in rats for Permethrin, Dermal LD50: >2000 mg/kg (rat), Oral LD50: >2000 mg/kg (rat), approx 783 mg/kg in the rat (over 300 times the therapeutic dose in the dog), imidacloprid dermal dose: >5,000 mg/kg in ratsImidacloprid orally: 450 mg/kg in rats, flumethrin: ld50 oral rat (male) 258 mg/kg, ld50 dermal rat > 150 mg/kg, Lufenuron Orally: > 2,000 mg/kg in rats Milbemycin LD50 information unavailable Symptoms of tremors and incoordination result at 19 times recommended dose, www.comfortis4dogs.com (AcuGuard is a private label*), May promote seizures in dogs already predisposed to seizures, Puppies less than 14 weeks of age may experience a higher rate of vomiting. … * It repels and kill ticks, fleas and mosquitos in all of their life stages to help keep your family’s dogs healthy and your house pest-free—all at a fraction of the cost of K9 Advantix II. These products are available at licensed veterinary hospitals. and cats who weigh at least 2.6 lbs. This topical treatment keeps your pup free of itching bug bites for up to one month with a single application! Simparica might have the edge over Bravecto because liver flavor has been shown to be very useful with dogs. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. *Dogs over 123.0 lb should be administered the appropriate combination of chews. Read honest and unbiased product reviews from our users. That makes Bravecto ® a cost-effective option for keeping your pet protected as it also won't wash off. * VCA Animal Hospitals and Banfield Pet Hospitals market some products under their own hospital private label, made by the   same manufacterer as the original product. For use in dogs from 11 weeks of age and over 2kg For optimal control of tick and flea infestation, the Bravecto spot-on should be administered at 3 monthly intervals. Personally I have sold over 5,000 doses and I have had two dogs vomit and have not seen any other side effects. Wash hands thoroughly with soap and water immediately after use of the product. (active ingredients: fipronil, cyphenothrin or etophenprox, methoprene). For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Bravecto® for Cats in the US. My vet is keen on it. Fluralaner is an inhibitor of the arthropod nervous system. Reproductive Safety Study: Bravecto was administered orally to intact, reproductively- sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum label dose) on three to four occasions at 8-week intervals. In a well-controlled U.S. field study, a single dose of Bravecto reduced fleas by ≥ 99.7% for 12 weeks. Updated: 2020-12-31. The specific warning was to be aware of the potential for neurological side-effects, including seizures. It kills and repels ticks, all life stages of fleas, and mosquitoes on contact before they bite and cause problems for your dog. It provides the same protection as K9 Advantix® II* but at a price that is far more affordable. In a well-controlled field study Bravecto was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics, and steroids. Every effort has been made to ensure the accuracy of the Bravecto information published above. Bravecto for Dogs has been proven safe for puppies over 8 weeks old, weighing at least 2 kg along with breeding, pregnant and lactating dogs. It may look like the pet has more fleas. Bravecto demonstrated ≥90% effectiveness against Amblyomma americanum 72 hours post-infestation for 8 weeks, but failed to demonstrate ≥90% effectiveness beyond 8 weeks. Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. One chew provides broad-spectrum and long-lasting protection that starts to kill fleas within 2 hours and controls 4 tick species: black-legged tick (a.k.a. It repels and kills ticks, fleas and mosquitoes in all life stages within 12 hours and for up to one month. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Bravecto should be administered topically as a single dose every 12 weeks according to the?Dosage Schedule. Diarrhea, mucoid and bloody feces were the most common observations in this study, occurring at a similar incidence in the treated and control groups. Provecta Advanced for Dogs is a one-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II* at a fraction of the cost. In a well-controlled U.S. field study, which included 294 dogs (224 dogs were administered Bravecto every 12 weeks and 70 dogs were administered an oral active control every 4 weeks and were provided with a tick collar); there were no serious adverse reactions. For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. All potential adverse reactions were recorded in dogs treated with Bravecto over a 182-day period and in dogs treated with the active control over an 84-day period. Provecta Advanced is a 5-way parasite treatment for dogs. The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting. deer tick), American dog tick, brown dog tick, and lone star tick. While it has been tested on younger dogs without adverse effects, Bravecto is not recommended for young puppies. The edema improved progressively through the day and had resolved without medical intervention by the next morning. Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness). Bravecto’s is just called a “tasty chew” and should mimic the generic taste of most dog treats. A study shows that 91 percent of canines happily take the medication. So Provecta for Cats, while being a cheaper option, tends to get more favorable ⭐ reviews than the $19 Provecta Advanced, as seen on the chart below. TRUSTED PROTECTION. Compared to other products which must be given every month. Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. History of seizures, must give with food. Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. Bravecto should be administered orally as a single dose every 12 weeks according to the Dosage Schedule below to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight. Five of the twelve treated dogs that experienced one or more of these signs did so within 6 hours of the first dosing. For topical use only. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. A single Bravecto ® Chew treatment lasts for 12 weeks in dogs, while the Spot-On lasts for 4 months for ticks and 6 months for fleas. * Imidacloprid & Permethrin. Provecta contains the same active ingredients as K9 Advantix II. Product doses are typically <100mg per dose. Wash hands after using product, as it is irritating to your eyes. Palatability: In a well-controlled U.S. field study, which included 559 doses administered to 224 dogs, 80.7% of dogs voluntarily consumed Bravecto within 5 minutes, an additional 12.5% voluntarily consumed Bravecto within 5 minutes when offered with food, and 6.8% refused the dose or required forced administration. If you would like to know why we haven’t included over the counter products (as would be sold in a grocery or pet supply store), click here. All lab data collected from all dogs was normal. Copyright © 2014 Intervet Inc, a subsidiary of Merck & Company Inc. Provecta Advanced provides one full month of protection for your dog in a convenient monthly application. 3850 Grand View Blvd.Los Angeles, CA  90066, www.zoetisus.com/products/pages/revolution_pet/revolutionpet.aspx, Inspired by the VIN community, part of the VIN family. Bravecto Chews is the first oral chew for dogs to provide up to 12 weeks of protection against fleas and ticks. Imidacloprid. Selamectin: >1,600 mg/kg in rats. Bravecto is a convenient tasty chewable tablet that kill fleas, prevent flea infestations, and kill ticks, such as black-legged (deer) ticks, American dog ticks, and brown dog ticks. Bravecto doesn’t have a chewable for cats, only dogs. The dogs in the control group (0X) were untreated. 7 weeks, 4 lbs or larger. The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels (gamma-aminobutyric acid (GABA)-receptor and glutamate-receptor). Speed of action – Bravecto begins killing fleas within 2 hours, and kills most ticks within 12 hours. The originating document has been archived. May promote seizures in dogs already predisposed to seizures. One dog in the 1X treatment group vomited food 4 hours following the first treatment. It also repels biting flies and kills chewing lice. Treatment with Bravecto may begin at any time of the year and can continue year round without interruption. Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. Flea killing ingredient; Flea sterilizing or additional ingredients; For dogs or cats; Youngest age or size approved for use; Waterproof or water resistant, Approved for pregnancy or lactation (nursing); How long until maximum effect against fleas is reached; Other parasites killed, controlled or repelled; How often applied or administered, Oral or Topical, Prescription drug, non-prescription drug or insecticide; LD50 (lethal dose to 50% of the population), Year first made available in U.S.; Manufacturer, Manufacturer’s website; Additional cautions, Flea Sterilizing or Additional Ingredients, Vectra 3D, SimpleGuard 3*, FirstShield Trio*, Vectra for Cats, SimpleGuard for Cats*, FirstShield for Cats*, Selamectin is waterproof, Suralaner is water resistant, Advantage II, Combiva, Crossblock II, Paradefense for cats, Provecta for cats, K9Advantix II, Paradefense for dogs, Provecta for dogs, Imoxi, Waterproof but wait 24 hours before bathing or swimming, Frontline Fiproguard, PetArmor, EasySpot (cats) Parastar (dogs) Effipro (cats), Frontline Plus, Fiproguard Plus, PetArmor Plus, Ectoadvance Plus, Indoxacarb both kills and sterilizes fleas, puppies 8 weeks and 4 lbs, kittens 8 weeks and 2 lbs, Waterproof (wait 24 hours before swimming/bathing), 7 weeks old and 18 lbs for dogs,10 weeks for kittens, Lufenuron (flea sterilizer) & Milbemycin (for add’l parasites), Approved for Pregnancy and Lactation (nursing). 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